Our commitment to people with muscle diseases
Dyne Therapeutics is a clinical-stage muscle disease company focused on advancing innovative life-transforming therapeutics for people living with genetically driven diseases. With its proprietary FORCE platform, Dyne is developing modern oligonucleotide therapeutics that are designed to overcome limitations in delivery to muscle tissue. Dyne has a broad pipeline for serious muscle diseases, including clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and a preclinical program for facioscapulohumeral muscular dystrophy (FSHD). For more information, please visit Dyne Therapeutics .
Role Summary:
The Senior Director, Toxicology is a key member of preclinical development teams and is responsible for the strategic planning and execution of nonclinical safety plans of Dyne’s portfolio programs supporting late discovery through first-in-human and proof-of-concept clinical studies of investigational therapeutics consisting of targeting antibodies conjugated with a variety of oligonucleotide and protein payloads to treat serious neuromuscular diseases. The person in this role must possess an in-depth understanding of regulatory guidance as they pertain to the nonclinical development of novel therapeutics along with documented experience designing and critically evaluating results of exploratory and GLP-compliant toxicology studies. Previous experience in authoring and reviewing nonclinical regulatory documents as well as interactions with regulatory authorities is required. This individual should have experience in the nonclinical safety assessment of therapeutic antibodies and/or oligonucleotides. The ability to work collaboratively with cross-functional teams is critical for this position.
This role is based in Waltham, MA without the possibility of being a remote role.
Primary Responsibilities Include:
Education and Skills Requirements:
Dyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.
#J-18808-Ljbffr...keywords and evergreen content. Those articles will cover a wide range of topics, from classic shows to the newest streaming TV networks (NBC, ABC, CBS, FOX, etc.) to streaming (Netflix, Apple, Hulu, etc), as well as hidden gems in entertainment, fandoms (popular topics...
...private medical group in Manhattan seeking Nurse Practitioner or Physician Assistant. Client seeking a dedicated and experienced Endocrinology Nurse Practitioner or Physician Assistant to join our healthcare team. Job Function Diagnosing and treating a variety of...
PPC SpecialistThis is a remote position approximately 5 - 7 hours per week.Help support and manage Pay Per Click campaigns, mainly with Google Adwords. In addition to making tweaks, help with the running of campaigns based on analytical data for further improvement...
...are the core values we live by in order to provide dynamic guest service at the Talkeetna Alaskan Lodge. As the Food and Beverage Administrator, you will provide office services while working closely with the staff in an efficient, courteous and dedicated manner. You will...
...Job Description Job Description Salary: $0.00-$0.00 Loving heart? Called to serve? Constellation Hospice is looking for volunteers to visit patients who have a terminal illness. Make a difference in your community, be part of the hospice team, and have a flexible...